PDO threads are made from Polydiaxanone suture material that has been used in surgical procedures, such as cardiac, osteopathic and plastic surgery for decades. Hypoallergenic and non-pyrogenic, PDO threads are a safe and effective way to lift and tighten sagging skin. Once inserted into the skin, the threads will instantly lift loose skin and continuously stimulate neocollagenesis to improve skin texture, fine lines and wrinkles and the overall firmness of the skin.